Melatonin in septic shock: some recent concepts.
2010-12 Srinivasan V, Pandi-Perumal SR, Spence DW, Kato H, Cardinali DP
Melatonin is a versatile molecule, synthesized not only in the pineal gland, but also in many other organs. Melatonin plays an important physiologic role in sleep and circadian rhythm regulation, immunoregulation, antioxidant and mitochondrial-protective functions, reproductive control, and regulation of mood.