Latest Facts
Medical Studies on Melatonin – Latest Facts

You want to get a fast overview on the latest research on melatonin and its multiple applications? – In this category you will find the most important studies listed separately; of course, these are also assigned to the respective subject areas.
The selection of the presented papers was made by the scientific committee of Interchron, the international forum for chronobiology, and it will be updated continuously.
Medical Studies on Melatonin – Latest Facts
Patients with malignant tumors often experience fluctuations in the severity of their symptoms depending on the time of day. In
Background: To investigate the association between melatonin levels and bone mineral density (BMD) in postmenopausal women with type 2 diabetes mellitus
Background: Asthma frequently co-occurs with anxiety and depression, yet the mechanisms underlying this lung-brain comorbidity remain elusive. The gut-lung-brain axis has
Type 2 Diabetes (T2D) is characterized by the toxic aggregation of human islet amyloid polypeptide (hIAPP or amylin) within pancreatic
In spite of the improvement of obstetric care, hypertensive disorders of pregnancy have continued to emerge as the major causes
Background: Diabetes mellitus is a global health challenge characterized by oxidative stress (OS) and persistent inflammation, which contribute to the progression
The aim of this study is to investigate the effects of melatonin on the left ventricular (LV) function in persistent
Aims: Colitis and its associated bone loss are major global health concerns with limited therapeutic options. Portulaca oleracea L. polysaccharide (POP)
Objective: Fibrocystic breast disease (FBD) is a prevalent benign breast disorder primarily affecting women of reproductive age. Characterized by breast pain
Melatonin and stress Melatonin and its metabolites are ubiquitous antioxidants that are produced in response to reactive oxygen species (ROS) in
Migraine is a chronic disease of global concern, regardless of socio-economic and cultural background. It most often and intensely affects
A variety of organisms including mammals have evolved a 24h, self-sustained timekeeping machinery known as the circadian clock (biological clock),
Background: As an infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the common signs of coronavirus disease
Objective: The prevalence of sleep disorders during the perinatal period is high and large health administrative database surveys have shown that
Recent studies revealed that non-coding RNAs (ncRNAs) play a crucial role in pathophysiological processes involved in diabetic cardiomyopathy (DCM) that
Microglial activation and melatonin protection have been reported in diabetic retinopathy (DR). Whether melatonin could regulate microglia to protect the
In type 2 diabetes mellitus (T2DM) and its related disorders like obesity, the abnormal protein processing, oxidative stress and proinflammatory
Melatonin is an ancient molecule that originated in bacteria. When these prokaryotes were phagocytized by early eukaryotes, they eventually developed
Aims: To evaluate the efficacy and safety of melatonin for migraine prophylaxis in adults. Methods: After a comprehensive literature search in the MEDLINE,
Melatonin is the main hormone involved in the control of the sleep-wake cycle. It is easily synthesisable and can be