biological rhythms

Medical Studies on Melatonin

Melatonin Synthesis and Function: Evolutionary History in Animals and Plants.

2020-04 Zhao D, Yu Y, Shen Y, Liu Q, Zhao Z, Sharma R, Reiter RJ

Melatonin is an ancient molecule that can be traced back to the origin of life. Melatonin's initial function was likely that as a free radical scavenger. Melatonin presumably evolved in bacteria; it has been measured in both α-proteobacteria and in photosynthetic cyanobacteria.

Poor sleep quality associates with self-reported psychiatric and cardiometabolic symptoms independently of sleep timing patterns in a large sample of rural and urban workers.

2020-01 Carvalho FG, Cunha AMD, Tonon AC, Pereira FDS, Matte U, Callegari-Jacques SM, Hidalgo MP

Poor sleep associates with mental and cardiometabolic pathological outcomes. The participation of sleep timing features in the pathways by which this relationship occurs is not clear.

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