Plasticity of glucose metabolism in activated immune cells: advantages for melatonin inhibition of COVID-19 disease
COVID-19 has infected hundreds of thousands and killed tens of thousands of people worldwide and it continues to ravage societies as well as fiscal and economic stability of several countries. Currently, several drugs that were designed for other conditions have been repurposed to counter the COVID-19 pandemic. Some have modest efficacy in resisting this disease, but all of them have significant toxicity. Several pharmaceutical companies are rushing to develop vaccines, but their availability is 8 to 12 months in the future. In the meantime, readily available and affordable molecules that will have utility as COVID-19 antidotes are being sought.