Pregnancy
Medical Studies on Melatonin – Pregnancy
Melatonin is essential for embryonic and foetal development because it has different functions for the unborn child, which only receives the mother’s melatonin directly via the placenta. If the mother’s melatonin production is impaired for whatever reason, this can also have an impact on the unborn child.
The placenta as the main supply channel
The placenta plays an extremely important role during pregnancy as it is the main supply channel for the child. If there are complications during the pregnancy, the placenta is usually expected to be involved somehow – sometimes with dramatic consequences for the mother and child, for example pre-eclampsia. A sufficient supply of melatonin from the mother can help here.
Melatonin for pre-eclampsia
Older studies have observed that women with pre-eclampsia exhibited substantially diminished melatonin values compared to healthy women. The placenta of these women also showed a low melatonin level and was therefore exposed to toxins. The anti-oxidative effect of melatonin allows it to protect the placenta from free radicals, which are toxic in cases of pre-eclampsia, and control the blood pressure of the pregnant woman.
Melatonin supports embryonic development
Melatonin is also a key regulator in the foetal development process. It not only helps the unborn child to form their own circadian rhythm, but also has a direct effect on the development of the nervous and endocrine systems, protects the organs responsible for the metabolism of the unborn, and supports the development of the foetal SCN. If there is a melatonin deficiency, this may partly be the reason behind delayed effects such as ADHD.
Medical Studies on Melatonin – Neurodegeneration
2025-01-17
Objective: The prevalence of sleep disorders during the perinatal period is high and large health administrative database surveys have shown that
2020-02-11
Circadian rhythm plays an important role as our internal body's clock that synchronizes behavior and physiology according to the external
2019-12-03
The development of the endometrium is a cyclic event tightly regulated by hormones and growth factors to coordinate the menstrual
2019-11-14
Several novel animal studies have shown that intrauterine metabolic programming can be modified in the event of reduced melatonin synthesis
2019-10-12
Melatonin has been shown to reduce oxidative stress and mitigate hypercoagulability. We hypothesized that maternally administered melatonin may reduce placental
2019-09-13
Pregnancy is influenced by the circadian ("circa" or approximately; diēm or day) system, which coordinates physiology and behavior with predictable
2019-06-13
Daily rhythms generated by endogenous circadian mechanisms and synchronized to the light-dark cycle have been implicated in the timing of
2019-04-14
Successful pregnancy requires adaptation in maternal physiology. During intrauterine life the mother's circadian timing system supports successful birth and postnatal
2018-09-03
Melatonin is a lipophilic hormone synthesized and secreted mainly in the pineal gland, acting as a neuroendocrine transducer of photoperiodic
2007-01-10
Pineal melatonin regulates circadian rhythms and influences sleep. Melatonin also has protective actions against tissue damage from free-radicals and other