Cardiovascular System
Medical Studies on Melatonin – Cardiovascular System
Melatonin plays a key role in cardiovascular health, for example in relation to arteriosclerosis, high blood pressure, coronary heart disease and heart attacks. This hormone has also proven to be a promising treatment method for stroke.
Melatonin as a blood pressure regulator
High blood pressure and the constriction of the blood vessels that this entails may have fatal consequences if the key organs are no longer sufficiently supplied with blood and can therefore no longer be supplied with enough oxygen. The result is a substantial increase in the risk of heart attack or stroke. Studies have demonstrated that melatonin reduces both blood pressure and vascular stiffness and therefore has very positive effects on cardiovascular health.
Melatonin reduces cell damage
Thanks to its highly anti-oxidative and anti-inflammatory properties, melatonin can also significantly reduce the extent of cell damage that often occurs after a heart attack or stroke. Free radicals in particular can affect the severity of these medical emergencies, because the tissue damage that they cause is irreparable.
Protection from dangerous oxidative stress
Melatonin has proven to be highly efficient both in preventing and treating acute diseases. It protects against oxidative stress and establishes a balance between pro-inflammatory and anti-inflammatory cytokines, and can, for example, in the event of a heart attack, even protect the heart from injury after myocardial ischaemia or during essential reperfusion.
Medical Studies on Melatonin – Cardiovascular System
2025-01-17
Cardiovascular diseases (CVDs) are the leading global cause of mortality and disability, tending to happen in younger individuals in developed
2025-01-17
Background: Matrix metalloproteinase-9 (MMP-9) is crucial in tissue remodeling after an adverse cardiac event. In experimental studies, melatonin has been found
2025-01-17
The prevention of cardiac life-threatening ventricular fibrillation and stroke-provoking atrial fibrillation remains a serious global clinical issue, with ongoing need
2025-01-17
The vascular endothelium is vital in maintaining cardiovascular health by regulating vascular permeability and tone, preventing thrombosis, and controlling vascular
2025-01-15
In recent days, the hike in obesity-mediated epidemics across the globe and the prevalence of obesity-induced cardiovascular disease has become
2025-01-15
Cardiovascular diseases (CVD) are among the leading causes of death worldwide. Many lines of evidence suggest that the disturbances in
2025-01-09
The topic of human circadian rhythms is not only attracting the attention of clinical researchers from various fields but also
2025-01-09
Cardiovascular disease is the cause of physical infirmity and thousands of deaths annually. Typically, during heart failure, cardiomyocyte mitochondria falter
2022-06-20
The pineal gland is a neuroendocrine gland which produces melatonin, a neuroendocrine hormone with critical physiological roles in the circadian
2021-02-18
Melatonin possesses multi-organ and pleiotropic effects with potency to control angiogenesis at both molecular and cellular levels. To date, many
2020-06-23
The mechanism for SARS-CoV-2 infection is the requisite binding of the virus to the membrane-bound form of angiotensin-converting enzyme 2
2020-05-15
This study evaluated the effects of melatonin supplementation on parameters of mental health, glycemic control, markers of cardiometabolic risk, and
2020-04-03
Melatonin is a hormone produced by the pineal gland, and it has extensive beneficial effects on various tissue and organs;
2020-01-03
Poor sleep associates with mental and cardiometabolic pathological outcomes. The participation of sleep timing features in the pathways by which
2019-11-04
Research focus recently shifted to mitochondrial dynamics and the role of fusion and fission in cardioprotection. The aim of this
2019-10-25
Melatonin, the receptors for which are abundant in the hypothalamic paraventricular nucleus (PVN), can protect the heart from myocardial ischemia-reperfusion
2019-09-02
In this review we summarized the actual clinical data for a cardioprotective therapeutic role of melatonin, listed melatonin and its
2019-07-12
The shortage of donor hearts could be alleviated with the use of the allografts from donation after circulatory death (DCD).
2019-07-01
Last year melatonin was 60 years old, or at least its discovery was 60 years ago. The molecule itself may
2018-07-14
Heart failure is a multifactorial clinical syndrome characterized by the inability of the heart to pump sufficient blood to the