sleep quality

Medical Studies on Melatonin

Blood melatonin level can serve as a potential biomarker for prostate and hepatocellular carcinomas

2021-03 Sartorelli L, Neto RJ, Moscheta-Pinheiro M, de Castro T, Fernandes F, Silva R, Novais A, Chuffa LG, Reiter R, Zuccari DA

Many systemic functions display circadian rhythms driven by an endogenous mechanism that is regulated by circadian-related genes and these gene expressions control a central clock in the brain and subordinate clocks in peripheral tissues. However, modern life has introduced environmental factors that often interfere with natural circadian rhythms. Importantly, circadian disruption has been identified as an independent risk factor of cancers.

Clinical Impact of Melatonin on Breast Cancer Patients Undergoing Chemotherapy; Effects on Cognition, Sleep and Depressive Symptoms: A Randomized, Double-Blind, Placebo-Controlled Trial.

2020-04 Palmer ACS, Zortea M, Souza A, Santos V, Biazús JV, Torres ILS, Fregni F, Caumo W

This randomized, double-blinded, placebo-controlled trial tested the hypothesis that 20mg of melatonin before and during the first cycle of adjuvant chemotherapy for breast cancer (ACBC) reduced the side effects associated with cognitive impairment.

The effect of prolonged-release melatonin on sleep measures and psychomotor performance in elderly patients with insomnia.

2009-09 Luthringer R, Muzet M, Zisapel N, Staner L

Objectives of this study were to investigate the effects of prolonged-release melatonin 2 mg (PRM) on sleep and subsequent daytime psychomotor performance in patients aged > or =55 years with primary insomnia, as defined by fourth revision of the Diagnostic and Statistical Manual of Mental Disorders of the American Psychiatric Association.

Categories

Scroll to Top