shift work

Medical Studies on Melatonin

Reduced melatonin synthesis in pregnant night workers: Metabolic implications for offspring.

2019-11 Nehme PA, Amaral F, Lowden A, Skene DJ, Cipolla-Neto J, Moreno CRC

Several novel animal studies have shown that intrauterine metabolic programming can be modified in the event of reduced melatonin synthesis during pregnancy, leading to glucose intolerance and insulin resistance in the offspring. It is therefore postulated that female night workers when pregnant may expose the offspring to unwanted health threats.

Melatonin profiles during the third trimester of pregnancy and health status in the offspring among day and night workers: A case series.

2019-04 Nehme PA, Amaral FG, Middleton B, Lowden A, Marqueze E, França-Junior I, Antunes JLF, Cipolla-Neto J, Skene DJ, Moreno CRC

Successful pregnancy requires adaptation in maternal physiology. During intrauterine life the mother's circadian timing system supports successful birth and postnatal development. Maternal melatonin is important to transmit circadian timing and day length to the fetus.

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