polysomnography

The effect of prolonged-release melatonin on sleep measures and psychomotor performance in elderly patients with insomnia.

Sleep /

Objectives of this study were to investigate the effects of prolonged-release melatonin 2 mg (PRM) on sleep and subsequent daytime psychomotor performance in patients aged > or =55 years with primary insomnia, as defined by fourth revision of the Diagnostic and Statistical Manual of Mental Disorders of the American Psychiatric Association.

The effect of prolonged-release melatonin on sleep measures and psychomotor performance in elderly patients with insomnia. Read More »

Randomized, double-blind clinical trial, controlled with placebo, of the toxicology of chronic melatonin treatment.

Basic facts, Sleep /

The objective of the present study was to assess the toxicology of melatonin (10 mg), administered for 28 days to 40 volunteers randomly assigned to groups receiving either melatonin (N = 30) or placebo (N = 10) in a double-blind fashion.

Randomized, double-blind clinical trial, controlled with placebo, of the toxicology of chronic melatonin treatment. Read More »

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