Melatonin-A Potent Therapeutic for Stroke and Stroke-Related Dementia2020-07 Sadanandan N, Cozene B, Cho J, Park YJ, Saft M, Gonzales-Portillo B, Borlongan CVSecreted by the pineal gland to regulate the circadian rhythm, melatonin is a powerful antioxidant that has been used to combat oxidative stress in the central nervous system.