Immune system

Immune system

A strong immune system is an essential factor in human health, because it helps to successfully fight viruses, bacteria and other micro-organisms, making it an important provider of protection against pathogens. It also affects wound healing and plays a key role in protecting against other diseases such as cancer. Melatonin is capable of regulating this complex system in such a way that it offers perfect protection while also not reacting excessively. To this end, it regulates both anti-inflammatory and pro-inflammatory factors, which in turn control immune cells.

Versatile protective mechanisms

Oxidative damage in particular has a severe impact on human health and has been identified as a key factor in the genesis and development of numerous diseases. Melatonin plays a key role in this context. As a natural antioxidant of the body, it offers important protection against free radicals, but it also has many indirect effects too. For example, melatonin activates anti-oxidative enzymes, providing support for DNA repair processes, among other things.

Melatonin reduces cell damage

As was recently confirmed by a study, melatonin is a highly effective agent for treating inflammatory and immune diseases by inhibiting toll-like receptors (TLRs). These are of fundamental importance in the pathophysiology of diseases associated with inflammation processes, including those related to neurodegenerative disorders and cancer. Other pro-inflammatory and anti-inflammatory factors are also positively affected by melatonin.

Melatonin is a pineal indolamine, allegedly known as a circadian rhythm regulator, and an antioxidative and immunomodulatory molecule. In both

In recent years, the role played by melatonin on the gut microbiota has gained increasingly greater attention. Additionally, the gut

The immune system is built to counteract unpredictable threats, yet it relies on predictable cycles of activity to function properly.

In all mammals, the circulating pool of MLTs is synthesized in the pineal gland during the night’s darkness hours. Its

Coronavirus disease 2019 (COVID‑19), a systemic illness caused by severe acute respiratory distress syndrome 2 (SARS‑CoV‑2), has triggered a worldwide

Circadian rhythms are present in almost all cells and play a crucial role in regulating various biological processes. Maintaining a

Coronavirus (SARS-CoV-2) is spreading rapidly in the world and is still taking a heavy toll. Studies show that cytokine storms

Coronavirus disease-19 (COVID-19) is a complex disease that causes illness ranging from mild to severe respiratory problems. It is caused

Treatment for coronavirus disease 2019 (COVID19) pneumonia remains empirical and the search for therapies that can improve outcomes continues. Melatonin

The pathogenesis of a COVID-19 respiratory infection, in a major way, is related to what is referred to as the

The coronavirus, COVID-19, has infected hundreds of thousands and killed tens of thousands of individuals worldwide. This highly infectious condition

An optimal recovery between training sessions is of similar if not greater importance as the training content and program of

Human Coronaviruses (HCoVs), including severe acute respiratory syndrome coronavirus (SARS-CoV), Middle east respiratory syndrome coronavirus (MERS-CoV), and 2019 novel coronavirus

This article summarizes the likely benefits of melatonin in the attenuation of COVID-19 based on its putative pathogenesis.

The current COVID-19 pandemic is one of the most devastating events in recent history. The virus causes relatively minor damage

In cancer cells, glucose is primarily metabolized to pyruvate and then to lactate in the cytosol.

This review summarizes published reports on the utility of melatonin as a treatment for virus-mediated diseases. Of special note are

From an evolutionary point of view, vitamin D and melatonin appeared very early and share functions related to defense mechanisms.

PAK1 (RAC/CDC42-activated kinase 1) is the major "pathogenic" kinase whose abnormal activation causes a wide variety of diseases/disorders including cancers,

Scroll to Top