Immune system
Medical Studies on Melatonin – Immune system
A strong immune system is an essential factor in human health, because it helps to successfully fight viruses, bacteria and other micro-organisms, making it an important provider of protection against pathogens. It also affects wound healing and plays a key role in protecting against other diseases such as cancer. Melatonin is capable of regulating this complex system in such a way that it offers perfect protection while also not reacting excessively. To this end, it regulates both anti-inflammatory and pro-inflammatory factors, which in turn control immune cells.
Versatile protective mechanisms
Oxidative damage in particular has a severe impact on human health and has been identified as a key factor in the genesis and development of numerous diseases. Melatonin plays a key role in this context. As a natural antioxidant of the body, it offers important protection against free radicals, but it also has many indirect effects too. For example, melatonin activates anti-oxidative enzymes, providing support for DNA repair processes, among other things.
Melatonin reduces cell damage
As was recently confirmed by a study, melatonin is a highly effective agent for treating inflammatory and immune diseases by inhibiting toll-like receptors (TLRs). These are of fundamental importance in the pathophysiology of diseases associated with inflammation processes, including those related to neurodegenerative disorders and cancer. Other pro-inflammatory and anti-inflammatory factors are also positively affected by melatonin.
Medical Studies on Melatonin – Immune system
2025-01-17
Melatonin is a pineal indolamine, allegedly known as a circadian rhythm regulator, and an antioxidative and immunomodulatory molecule. In both
2025-01-15
In recent years, the role played by melatonin on the gut microbiota has gained increasingly greater attention. Additionally, the gut
2025-01-09
The immune system is built to counteract unpredictable threats, yet it relies on predictable cycles of activity to function properly.
2025-01-09
In all mammals, the circulating pool of MLTs is synthesized in the pineal gland during the night’s darkness hours. Its
2025-01-09
Coronavirus disease 2019 (COVID‑19), a systemic illness caused by severe acute respiratory distress syndrome 2 (SARS‑CoV‑2), has triggered a worldwide
2025-01-09
Circadian rhythms are present in almost all cells and play a crucial role in regulating various biological processes. Maintaining a
2021-05-08
Coronavirus (SARS-CoV-2) is spreading rapidly in the world and is still taking a heavy toll. Studies show that cytokine storms
2021-04-01
Coronavirus disease-19 (COVID-19) is a complex disease that causes illness ranging from mild to severe respiratory problems. It is caused
2020-06-23
Treatment for coronavirus disease 2019 (COVID19) pneumonia remains empirical and the search for therapies that can improve outcomes continues. Melatonin
2020-06-04
The pathogenesis of a COVID-19 respiratory infection, in a major way, is related to what is referred to as the
2020-05-18
The coronavirus, COVID-19, has infected hundreds of thousands and killed tens of thousands of individuals worldwide. This highly infectious condition
2020-05-15
This study evaluated the effects of melatonin supplementation on parameters of mental health, glycemic control, markers of cardiometabolic risk, and
2020-05-06
An optimal recovery between training sessions is of similar if not greater importance as the training content and program of
2020-04-26
Human Coronaviruses (HCoVs), including severe acute respiratory syndrome coronavirus (SARS-CoV), Middle east respiratory syndrome coronavirus (MERS-CoV), and 2019 novel coronavirus
2020-04-26
This article summarizes the likely benefits of melatonin in the attenuation of COVID-19 based on its putative pathogenesis.
2020-04-19
The current COVID-19 pandemic is one of the most devastating events in recent history. The virus causes relatively minor damage
2020-04-18
In cancer cells, glucose is primarily metabolized to pyruvate and then to lactate in the cytosol.
2020-04-18
This review summarizes published reports on the utility of melatonin as a treatment for virus-mediated diseases. Of special note are
2020-04-13
From an evolutionary point of view, vitamin D and melatonin appeared very early and share functions related to defense mechanisms.
2020-04-13
PAK1 (RAC/CDC42-activated kinase 1) is the major "pathogenic" kinase whose abnormal activation causes a wide variety of diseases/disorders including cancers,