Clinical trials

Background: Asthma frequently co-occurs with anxiety and depression, yet the mechanisms underlying this lung-brain comorbidity remain elusive. The gut-lung-brain axis has

In spite of the improvement of obstetric care, hypertensive disorders of pregnancy have continued to emerge as the major causes

The aim of this study is to investigate the effects of melatonin on the left ventricular (LV) function in persistent

Objective: Fibrocystic breast disease (FBD) is a prevalent benign breast disorder primarily affecting women of reproductive age. Characterized by breast pain

Background: As an infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the common signs of coronavirus disease

Aims: To evaluate the efficacy and safety of melatonin for migraine prophylaxis in adults. Methods: After a comprehensive literature search in the MEDLINE,

Aims: Observational studies have shown that sleep pattern is associated with age-related macular degeneration (AMD), but whether sleep pattern is a

Background and aims: Melatonin is a ubiquitous hormone produced not only by the pineal gland but also by other organs and

The serotonergic pathway may impact the pathogenesis and the course of inflammatory bowel diseases (IBDs). The aim of this study

Suppressive therapy of recurrent genital herpes is a challenge, and melatonin may be an alternative. Objective: To evaluate the action of melatonin,

Purpose: Obstructive sleep apnea (OSA) is a common serious sleep disorder. Melatonin-based drugs such as agomelatine may have beneficial effects on

Coronavirus (SARS-CoV-2) is spreading rapidly in the world and is still taking a heavy toll. Studies show that cytokine storms

The role of melatonin has been extensively investigated in pathophysiological conditions, including autism spectrum disorder (ASD). Reduced melatonin secretion has

This study aimed to determine the effect of exogenous melatonin on the number of sedative drugs and the duration of

Alzheimer's disease (AD) is a degenerative disease that is characterized by massive neuron devastations in the hippocampus and cortex. Mild

This study evaluated the effects of melatonin supplementation on parameters of mental health, glycemic control, markers of cardiometabolic risk, and

An optimal recovery between training sessions is of similar if not greater importance as the training content and program of

This randomized, double-blinded, placebo-controlled trial tested the hypothesis that 20mg of melatonin before and during the first cycle of adjuvant

Sleep disorders and circadian dysregulation appear to be associated with primary headache disorders.

The imbalance between pro-oxidant and antioxidant systems often leads to further oxidative damage in the pathogenesis of both diabetes and