oocyte

Improvement of oocyte quality through the SIRT signaling pathway

Background: Oocyte quality is one of the major deciding factors in female fertility competence. Methods: PubMed database was searched for reviews by using the following keyword “oocyte quality” AND “Sirtuins”. The methodological quality of each literature review was assessed using the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) 2020 statement. Main findings: Oxidative stress has been

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Melatonin prevents postovulatory oocyte aging in the mouse and extends the window for optimal fertilization in vitro.

The quality of metaphase II oocytes deteriorates rapidly following ovulation as the result of an aging process associated with impaired fertilizing potential, disrupted developmental competence, and increased likelihood of embryonic resorption.

Melatonin prevents postovulatory oocyte aging in the mouse and extends the window for optimal fertilization in vitro. Read More »

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